A study of adhesion and molecular recognition based on magnetic colloids

Prof. Emanuel Bertrand
Laboratoire Colloïdes et Matériaux Divisés, UMR CNRS/Paris 6/ESPCI 7612, Paris, France

We use super-paramagnetic colloids to study adhesion and more particularly the kinetics of molecular recognition between a ligand and a receptor. I will first focus on the experimental study of polymer bridging. Then, our original method to follow the kinetics of association between biologically relevant molecules shall be introduced. Within this approach, we have shown that the confinement of molecules on surfaces strongly influences their recognition kinetics.